9.00-9.30am: Registration

9.30-11.00am

SESSION 1: Monoclonal antibodies – Biology and clinical practice

· Welcome and Introduction· Clinical perspective - Rheumatologist· Clinical pers. – Gastroenterologist· Counselling perspective (Mothersafe) 

11.30am-12.30pm

SESSION 2: Anticonvulsants and Folate Supplementation

· Valproate and other Anticonvulsants in pregnancy; including the role of folate supplementation.· Wider uses of anticonvulsants 

1.30pm-3.30pm

SESSION 3: Categorisation of Drugs during Pregnancy

· TGA perspective· FDA and Australian perspective 

Registration details· 

Cost is $120 ($80 for ABDS members)· Morning tea and lunch are provided (gluten free and vegetarian options available) 

Mental Health and Pregnancy

ABDS & PPMIS

Friday March 9, 2012

Royal Women’s Hospital, Melbourne

Invited Speakers

Dr Lisa Amir Senior Research Fellow Mother & Child Health Research Centre. La Trobe University Breastfeeding and drug therapy for mood disorder

Professor Anne Buist Professor of Women's Mental Health, University of Melbourne

Medications for the treatment of mood disorders in pregnancy

Heather Gilbert Monash Alfred Psychiatry Research Centre (MAPrc) Alfred Hospital, Melbourne, The National Register of Antipsychotic Medication in Pregnancy update

Luke Grzeskowiak U South Australia

Long-term effects on child growth following prenatal exposure to (SSRIs).

Fiona Judd  Director, Centre for Women’s Mental Health Clinical Director (Medical)

Anxiety and depression  during pregnancy

Deb Kennedy Director, Mothersafe

Review of counselling by an Australian teratology Information Service

Associate professor Terry O’Brien Royal Melbourne Hospital

The Australian Pregnancy Epilepsy Register

Powerpoints slides of some of the presentations are available.

Email Helen Ritchie if you are interested.

Planning Pregnancy and Preventing Birth defects

Invited international speakers: John Graham, Bob Brent

Invited national speakers: Frank Nicholas, Carol Bower, Bill Webster, Sandra Lowe, Neil Hotham, Kris Barlow-Stewart, Jane Halliday, Leeanda Wilton, Debra Kennedy, Pam Palasanthiran

Tribute to Marsh Edwards· 

• The role of hyperthermia in human birth defects – John Graham· 

• Birth and other defects in animals : continuing in the footsteps of Marsh Edwards – Frank NicholasTony Lipson

Lecture: The cause and prevention of Congenital Malformations – will we ever prevent this groups of diseases? Bob Brent 

New perspectives on old problems· 

• Alcohol

• Ionising radiation

• Dental care

• CMV

Fetal consequences of maternal conditions· 

• Obesity and pregnancy

• Diabetes and diabetic embryopathy

• Folic acid

Policy and Practice

• Drugs in pregnancy and planning pregnancy

• Genetics Education

• Prenatal diagnosis and screening

• PGD and preventing birth defects

• PLaN 

Obstetric Drug Information Services Workshop

Invited international speakers: Myla Moretti, Orna Diav-Citrin

Invited national speakers: Neil Hotham, Rodney Whyte, Judith Kristensen, Treasure McGuire, Tricia Taylor, Morna Falkland, Neil Hotham, Judith Kirby, Elizabeth Sullivan, Chris Schyvens, Alison Hitchcock/ Janet Graham, Lyn Colvin, Marie-Paule Austin, Cres Eastman, Ernest Somerville

Who’s who and what do we do

· Reports from South Australia, Victoria, Western Australia, Queensland, NSW (MotherSafe), ACT

Collaboration and cooperation

· Poisons                                                                                                                  

· Motherisk/OTIS                                                                                                   

· ENTIS                                                                                                                    

· NPSU                                                                                                                     

· TGA                                                                                                                       

Registries and follow-up

AED Registry                                                                                  

PBS medications and pregnancy outcome data- linkage in WA                        

Collection and Analysis of Drug safety Data in Pregnancy                                

Paroxetine and fluoxetine  in pregnancy                                                                                 

UPDATE IN CLINICAL TERATOLOGY

Tribute to Marsh Edwards:  Iodine deficiency—Cres Eastman

Tony Lipson Lecture: Pharmacotherapy in breastfeeding Myla Moretti

· Bioscience Ethics in the Mirror of Future Generations

· Influenza, fever, hyperthermia and the development of schizophrenia:  A hypothesis

· Vaccines in pregnancy

· Depression and antidepressants in pregnancy

· Valproate in pregnancy

· AED in pregnancy

Invited international speakers: Prof Ken Jones, Prof Judith Hall, Dr Tina Chambers

Tribute to Marsh Edwards: An approach to a child with birth defects – Ken Jones

· Alcohol

· Epigenetics

· Statins in pregnancy

· Complementary and medicines and folates

· SSRIs

Symposium – Embryo, fetus and newborn: from experiment to clinical practice and prevention in the Antipodes

· IVF, Embryonic stem cells

· Male reproductive health – Prof Gordon Baker

· Prenatal diagnosis –

· Genetic counselling:

· Maternity care

· Diethylstilboestrol

· Twins

· Hyperthermia

· Congenital rubella – A/Prof Paul Lancaster

Invited international speakers: Ken Jones,  Bengt Danielsson, Lorian Hayes, Tina Chambers, John Graham

Invited national speakers: Elizabeth Sullivan,  David Tudehope, Bill Webster, Neil Hotham, Helen Ritchie, Paul Lancaster, Jane Halliday

Tribute to Marsh Edwards: Craniofacial deformation in human infants – John Graham

Tony Lipson Lecture: Teratogenicity by hERG potassium channel blocking drug via embryonic arrhythmia and hypoxia-related mechanisms- Bengt Danielsson

Update on Drugs and Infections in Pregnancy

· Prescribing in pregnancy                                                   

· Use of teratogen information services in North America  

· Pregnancy and drug therapy: inadequacies of product information

· Counselling for alcohol in pregnancy

· Smoking and illicit drugs in pregnancy

· Complementary medicines in pregnancy

· New patterns of malformation in diabetic embryopathy

· Counselling about risks of fertility drugs and IVF

· Maternal age and birth defects in Victoria, 1983-2001

· Safety of medications to treat rheumatoid arthritis in pregnancy

· Teratogenicity of antiepileptic drugs

· Genetic counselling for oculo-auricular-vertebral sequence

· Pregnancy outcome among women who have asthma

invited international speakers: Ken Jones

Invited national speakers: Elizabeth Elliott, Sally Dunwoodie

Tribute to Marsh Edwards: The effect of folic acid on the Cited 2 mutant phenotype in mouse -Dr Sally Dunwoodie

Tony Lipson Lecture: Fetal alcohol syndrome: A 30 year experience -Prof. Ken Jones

Invited international speakers: Lewis Holmes, Tina Chambers

Invited national speakers:Les Sheffield, Carol Bower, Terry O’Brien, Marsh Edwards, Debbie Kennedy, Bill Webster, Helen Ritchie

Tony Lipson Lecture: Identification of human teratogens: principles and experiences—Dr Lewis Holmes

Marsh Edwards Lecture: Strengths and weaknesses of teratogen information service studies in evaluating human teratogenicity—Dr Tina Chambers

Update on Drugs and Infections in Pregnancy

· Initial experience of MotherSafe­the NSW Statewide Medications in Pregnancy and Lactation Advisory Service

· High body temperature during pregnancy; how high is too high and how long is too long?

· Maternal fever and pregnancy outcome

· Vitamins in pregnancy

· CVS as a cause of malformations: issues and arguments

· Hypoxia as a cause of cleft lip Human evidence of herbal safety in pregnancy

· Management of epilepsy in pregnancy

· Teratogenicity of anticonvulsants     

· Antidepressants in pregnancy

Invited international speakers: Dr Elisabeth Robert, Anne Pastuszak

Invited national speakers: Dr Barry Borman, Dr Carol Bower, Dr Dominic Dwyer, Dr Sandra Lowe, A/Prof Bill Webster, Dr Stephen Steigrad, Dr Debbie Kennedy

Tribute to Assoc. Prof. David Walsh

Tribute to Marsh Edwards: How to reconcile safe fetal development and maternal needs—Anne Pstuszak

Tony Lipson Lecture: Reproductive risk evaluation from clinical and public health perspectives-Elisabeth Robert

· Drugs in pregnancy-information sources

· Controversies in medications for nausea and vomiting

· Anticonvulsants

· Herbal remedies

Medical conditions in pregnancy

· Viral infections in pregnancy

· Diabetes

· Antidepressants

· Anti-cancer

· Male-mediated birth defects

· Fertility drugs

· Compliance in using folic acid to prevent neural tube defects

· Illicit drugs, substance abuse

Travelling in pregnancy

· Infections

· Drugs

· Vaccines

· Prescribing in pregnancy