February 2017
/Gestational nanomaterial exposures: microvascular implications during pregnancy, fetal development and adulthood.
A systematic review of literature encompassing nanoparticle exposure before, and during pregnancy as well as possible effects in adults. Possible mechanisms of action are described.
Maternal nutritional status as a contributing factor for the risk of fetal alcohol spectrum disorders.
Repro Toxicol (2016) 59:101-8.
This South African study compared the nutritional status of mothers of children with FAS. They found that most mothers were deficient in most micronutrients. Although control mothers had a higher BMI than FAS mothers. Maternal BMI is more significant for positive, food intake was similar. The authors conclude that any minor advantages in nutrient intake were overpowered by teratogenic effects of alcohol.
Serotonin and poor neonatal adaptation after antidepressant exposure in utero.
Acta Neuropsych (2017) 29:43-53.
Poor neonatal adaptation, such as restlessness, tremors or sleeping difficulties are observed in babies exposed to psychotropic medications in late gestation. This study included 63 infants exposed to selective antidepressants (SAD) in the last 2 weeks of pregnancy. The neonatal 5-hydroxyindoleacetid acid (5-HIAA) levels were followed for the first 3 days postpartum. 5-HIAA levels were higher in babies with poor neonatal adaptation on Day 1 compared to SAD-exposed infants who did not develop adaptation problems.